原著論文

2023

・Organocatalytic Access to Tetrasubstituted Chiral Carbons Integrating Functional Groups

 Asano, K.; Matsubara, S.
 Chem. Rec. 2023, 23, e202200200.

2022

・Non-Enzymatic Catalytic Asymmetric Cyanation of Acylsilanes

 Nagano, T.; Matsumoto, A.; Yoshizaki, R.; Asano, K.; Matsubara, S.
 Commun. Chem. 20225, 45.

2021

・Catalytic Asymmetric Cycloetherification via Intramolecular Oxy-Michael Addition of Enols

 Murata, R.; Asano, K.; Matsubara, S.
 Tetrahedron 202197, 132381.

 Highlighted in Organic Chemistry Highlights in Organic Chemistry Portal.

Multipoint Recognition of Molecular Conformations with Organocatalysts for Asymmetric Synthetic Reactions

 Asano, K.
 Bull. Chem. Soc. Jpn. 202194, 694–712.

 Selected as the inside cover.

2020

・Desymmetrization of gem-Diols via Water-Assisted Organocatalytic Enantio- and Diastereoselective Cycloetherification

 Murata, R.; Matsumoto, A.; Asano, K.; Matsubara, S.
 Chem. Commun. 202056, 12335–12338.

 Selected as the inside back cover.
 Highlighted in Synfacts 2020, 16, 1276.

trans-Cyclooctenes as Chiral Ligands in Rhodium-Catalyzed Asymmetric 1,4-Additions

 Nagano, T.; Einaru, S.; Shitamichi, K.; Asano, K.; Matsubara, S.
 Eur. J. Org. Chem. 2020, 7131–7133.

 Selected as the Very Important Paper (VIP).
 Selected as the Front Cover.
 Highlighted in Chemistry Views.

・Enantio- and Diastereoselective Construction of Contiguous Tetrasubstituted Chiral Carbons in Organocatalytic Oxadecalin Synthesis

 Wada, Y.; Murata, R.; Fujii, Y.; Asano, K.; Matsubara, S.
 Org. Lett. 202022, 4710–4715.

 Highlighted in Organic Chemistry Highlights in Organic Chemistry Portal.

2019

・Enantioselective Bromination of Axially Chiral Cyanoarenes in the Presence of Bifunctional Organocatalysts

 Wada, Y.; Matsumoto, A.; Asano, K.; Matsubara, S.
 RSC Adv20199, 31654–31658.

・Asymmetric syn-1,3-Dioxane Construction via Kinetic Resolution of Secondary Alcohols Using Chiral Phosphoric Acid Catalysts

 Matsumoto, A.; Asano, K.; Matsubara, S.
 Asian J. Org. Chem. 20198, 814–818.

Organocatalytic Enantio- and Diastereoselective Construction of syn-1,3-Diol Motifs via Dynamic Kinetic Resolution of In Situ Generated Chiral Cyanohydrins

 Matsumoto, A.; Asano, K.; Matsubara, S.
 Org. Lett. 201921, 2688–2692.

・Asymmetric Cycloetherification of in Situ Generated Cyanohydrins through the Concomitant Construction of Three Chiral Carbon Centers

 Kurimoto, Y.; Nasu, T.; Fujii, Y.; Asano, K.; Matsubara, S.
 Org. Lett. 201921, 2156–2160.

・Kinetic Resolution of Acylsilane Cyanohydrins via Organocatalytic Cycloetherification

 Matsumoto, A.; Asano, K.; Matsubara, S.
 Chem.—Asian J. 201914, 116–120.

 Selected as the Cover Feature.
 Selected as the top 10% most downloaded paper.

2018

trans-Cyclooctenes as Halolactonization Catalysts

 Einaru, S.; Shitamichi, K.; Nagano, T.; Matsumoto, A.; Asano, K.; Matsubara, S.
 Angew. Chem., Int. Ed. 201857, 13863–13867.

 Highlighted in Synfacts 201814, 1198.

・Asymmetric Cycloetherification by Bifunctional Organocatalyst

 Asano, K.; Matsubara, S.
 Synthesis 201850, 4243–4253.

・Catalytic Approaches to Optically Active 1,5-Benzothiazepines

 Asano, K.; Matsubara, S.
 ACS Catal. 20188, 6273–6282.

2017

Organocatalytic Enantio- and Diastereoselective Cycloetherification via Dynamic Kinetic Resolution of Chiral Cyanohydrins

 Yoneda, N.; Fujii, Y.; Matsumoto, A.; Asano, K.; Matsubara, S.
 Nat. Commun. 20178, 1397.

 Press release on Kyoto University website.
 Highlighted in Newspapers (Nikkei Shinbun & Kagaku Kogyo Nippo).
 Highlighted in Synform 20183, A33.
 Highlighted in Organic Chemistry Highlights in Organic Chemistry Portal.

・Asymmetric Net Cycloaddition for Access to Diverse Substituted 1,5-Benzothiazepines

 Fukata, Y.; Yao, K.; Miyaji, R.; Asano, K.; Matsubara, S.
 J. Org. Chem. 201782, 12655–12668.

 Highlighted in Abstracts in Organic Chemistry Portal.

・Bifunctional Organocatalysts for the Asymmetric Synthesis of Axially Chiral Benzamides

 Miyaji, R.; Wada, Y.; Matsumoto, A.; Asano, K.; Matsubara, S.
 Beilstein J. Org. Chem. 201713, 1518–1523.

Induction of Axial Chirality in 8-Arylquinolines through Halogenation Reactions Using Bifunctional Organocatalysts

 Miyaji, R.; Asano, K.; Matsubara, S.
 Chem.—Eur. J. 201723, 9996–10000.

 Selected as the Inside Cover.

2016

・穏和な有機触媒がもたらす精密不斉合成

  Asano, K.
 有機合成化学協会誌 201674, 1194–1205.

・Asymmetric Cycloetherification via the Kinetic Resolution of Alcohols Using Chiral Phosphoric Acid Catalysts

  Yoneda, N.; Matsumoto, A.; Asano, K.; Matsubara, S.
 Chem. Lett. 201645, 1300–1303.

2015

・Asymmetric Synthesis of Spiroketals with Aminothiourea Catalysts

 Yoneda, N.; Fukata, Y.; Asano, K.; Matsubara, S.
 Angew. Chem., Int. Ed. 201554, 15497–15500.

 Highlighted in Synfacts 201612, 89.

・穏やかな触媒がもたらす精密有機合成

 Asano, K.
 化学と工業 201568, 832–833.

・Diastereoselective Reduction of β-(1,3-Dioxan-4-yl)ketones

 Matsumoto, A.; Asano, K.; Matsubara, S.
 Synlett 201526, 1872–1874.

・A Chiral Phosphoric Acid Catalyst for Asymmetric Construction of 1,3-Dioxanes

 Matsumoto, A.; Asano, K.; Matsubara, S.
 Chem. Commun. 201551, 11693–11696.

・Bifunctional Organocatalysts for the Enantioselective Synthesis of Axially Chiral Isoquinoline N-Oxides

 Miyaji, R.; Asano, K.; Matsubara, S.
 J. Am. Chem. Soc. 2015137, 6766–6769.

Facile Net Cycloaddition Approach to Optically Active 1,5‑Benzothiazepines

 Fukata, Y.; Asano, K.; Matsubara, S.
 J. Am. Chem. Soc. 2015137, 5320–5323.

 Highlighted in Synfacts 201511, 770.
 Highlighted in J. Synth. Org. Chem., Jpn. 201573, 1162.

2014

・Asymmetric Oxy-Michael Addition to γ-Hydroxy-α,β-Unsaturated Carbonyls Using Formaldehyde as an Oxygen-Centered Nucleophile

 Yoneda, N.; Hotta, A.; Asano, K.; Matsubara, S. 
 Org. Lett. 201416, 6264–6266.

・Asymmetric Isomerization of ω-Hydroxy-α,β-Unsaturated Thioesters into β-Mercaptolactones by a Bifunctional Aminothiourea Catalyst

 Fukata, Y.; Okamura, T.; Asano, K.; Matsubara, S.
 Org. Lett. 201416, 2184–2187.

・Asymmetric chroman synthesis via an intramolecular oxy-Michael addition by bifunctional organocatalysts

 Miyaji, R.; Asano, K.; Matsubara, S.
 Org. Biomol. Chem. 201412, 119–122.

2013

・Procedure-Controlled Enantioselectivity Switch in Organocatalytic 2-Oxazolidinone Synthesis

 Fukata, Y.; Asano, K.; Matsubara, S.
 J. Am. Chem. Soc. 2013135, 12160–12163.

・Asymmetric Indoline Synthesis via Intramolecular Aza-Michael Addition Mediated by Bifunctional Organocatalysts

 Miyaji, R.; Asano, K.; Matsubara, S.
 Org. Lett. 201315, 3658–3661.

・Asymmetric Cycloetherifications by Bifunctional Aminothiourea Catalysts: The Importance of Hydrogen Bonding

 Fukata, Y.; Miyaji, R.; Okamura, T.; Asano, K.; Matsubara, S.
 Synthesis 201345, 1627–1634.

・Asymmetric Synthesis of 1,3-Oxazolidines via Intramolecular Aza-Michael Addition by Bifunctional Organocatalysts

 Fukata, Y.; Asano, K.; Matsubara, S.
 Chem. Lett. 201342, 355–357.

2012

・Organocatalytic asymmetric oxy-Michael addition to a γ-hydroxy-α,β-unsaturated thioestervia hemiacetal intermediates

 Okamura, T.; Asano, K.; Matsubara, S.
 Chem. Commun. 201248, 5076–5078.

・Asymmetric Synthesis of 1,3-Dioxolanes by Organocatalytic Formal [3 + 2] Cycloaddition via Hemiacetal Intermediates

 Asano, K.; Matsubara, S.
 Org. Lett. 201214, 1620–1623.

2011

・Asymmetric Catalytic Cycloetherification Mediated by Bifunctional Organocatalysts

 Asano, K.; Matsubara, S.
 J. Am. Chem. Soc. 2011133, 16711–16713.